|Note||Please send message to our email or skype directly,|
in case of the platform system problem.
|Contact Information||Email: firstname.lastname@example.org|
|Targeted weight Loss||Focus on waist, belly and the position where fat easily accumulated|
Function: Slimming, Regulate blood fat, Toxin removal, Skin
|Storage||Sealed in a cool dry place|
|Shelf life||24 months|
|How to take Slimming Capsules||1 capsule a day before or after breakfast. Do not take more
capsules than recommended.|
Drink more water and eat more fruit if thirsty (not enough pure
water in your body reduces the body's glucose level in the blood,
which causes weakness and dizziness).
Do not skip meals (especially breakfast or lunch). It is important
while taking this product to maintain a healthy and balanced diet,
including pure water and natural juices.
Do not consume alcohol while taking Slimming Capsules. It may
neutralize the effectiveness of the slimming process.
Reduce 15 MG Slimming loss weight
1 pack have 10 pills
1 box have 10 packs
Each capsules of Reduce 15mg contains
SIBUTRAMINE belong to the category of appetite suppressant.
The Structural Formula:
Molecular Formula: C17H26ClN
Molecular Weight: 279.85 g/mol
Mechanism Of Action
Inhibits reuptake of norepinephrine, serotonin, and dopamine. May
stimulate satiety center in brain, causing appetite suppression.
Inhibits reuptake of Serotonin(5. H.T) nor adrenaline and to a
lesser extent, dopamine in Vivo and in vitro M1 and M2 Metabolite
are pharmacologically active and are up to about 100-fold more
potent reuptake inhibitors than sibutramine has no effects on
dopamine receptors, some thermogenic activity is evident at doses
of 10mg apparent low abuse potential in humans. Reduce
(Sibutramine) produce its therapeutic effect by Norepinephrine,
Serotonin and dopamine reuptake inhibition.
Reduce reaches maximum therapeutic concentration in 1.2hrs. Food delays the absorption by
3hrs. Approximately 77% of the single oral dose is absorbed. Steady
state reached with in 4days. Reduce (Sibutramine) is extensively
bound and is rapidly and extensively distributed into tissue. It
undergoes extensive first pas metabolism and is primarily by
cytochromep4503A4 isoenzyme. Approximately 85% of the drug
eliminated through urine.
Management of obesity, including weight loss and maintenance of
weight loss and should be used in conjugation with a reduced
calorie diet. Contra Indications
Pregnancy and paediatric patients, hypersensitivity, patients
receiving MAO inhibitors, anorexia, nervosa, patients taking other
centrally acting appetite suppressant drug.
Should not be taken with mao inhibitors, and drugs that may raise
blood pressure or heart rate. Should not be taken along with
ephidrine, phenyl propanolamine.
Dry mouth, anorexia, constipation, insomnia, dizziness.
Monitor BP regularly when prescribing sibutramine.
Its recommended for obese patients with an initial BMI 30kg/m2 or
27kg/m2 in the presence of the risk factors(e. g. Hypertension,
diabetes, dyslipidemia). Initially 10mg of sibutramine is given
once daily with or without food. If there is inadequate weight
loss, the dose may be titrated after four weeks to a total of 15mg
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